Yexel Exams: Leading Pharmacy Exam Prep in Australia for KAPS – Bridge Your Career Transition from India

Course Content
Heart Failure
0/12
Background
Anatomy and physiology of heart
Drug that exacerbate heart failure
Compensatory mechanisms and its complications
Clinical uses of Beta blockers
Therapeutical approach to manage heart failure
Agent that increases ejection fraction by directly stimulating cardiac contractility
Agent that increases ejection fraction by relaxing peripheral blood vessels
Increasing ejection fraction by affecting cardiac remodelling process
Clinical uses of Beta blockers
Summary of drugs used in heart failure
Recalls and expected questions.
Heart Failure
DISEASE    DRUG(s) MECHANISM OF ACTION
HypertensionLabetalol (by injection)↓ cardiac output
Atenolol, Bisoprolol>↓ Renin and RASS system
Metoprolol, PropranololInhibition of presynaptic NE release
Inhibition of sympathetic outflow in 
CNS
Treatment of hypertensive pregnant 
and hypertensive crisis
Cardiac ArrhythmiasEsmolol (ultrashort
Acting T ½ = 10 min),
Atenolol, Propranolol

(Bisoprolol and carvedilol are preferred) 		Propranolol: Membrane stabilization
(Block Na channel → local 
anaesthetic effect/antiarrhythmic
↓ conductivity
Treatment of supraventricular and Ventricular arrhythmias
Angina PectorisBeta blockers, 
Eg. Propranolol		Anti-ischemic action: ↓heart-rate,
↓cardiac work and oxygen demand
↓the frequency of angina episodes
Previous
Next